Pheochromocytoma-Paraganglioma: Translational Approach from Genetics to Clinical Neuroendocrinology
نویسندگان
چکیده
منابع مشابه
Genetics of pheochromocytoma and paraganglioma in Spanish pediatric patients.
Pheochromocytomas and paragangliomas are neuroendocrine tumors developed in the adrenal medulla and in the extra-adrenal thoraco-abdominal sympathetic and parasympathetic paraganglia, respectively. Although clinical diagnosis of these tumors is infrequent during childhood, there have been reports of pediatric patients either carrying germline alterations in one of ten major pheochromocytoma/par...
متن کاملVon Hippel-Lindau and Hereditary Pheochromocytoma/Paraganglioma Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Von Hippel-Lindau disease (vHL) is a hereditary tumor predisposition syndrome that places affected individuals at risk for multiple tumors, which are predominantly benign and generally occur in the central nervous system or abdomen. Although the majority of tumors occur in adults, children and adolescents with the condition develop a significant proportion of vHL manifestations and are vulnerab...
متن کاملPrimary Cardiac Pheochromocytoma (Paraganglioma)
Pheochromocytomas are catecholamine-producing neuroendocrine tumors arise from primitive neural crest cells. About 90% of these tumors occur as solitary benign tumors of the adrenal medulla, where majority of chromaffin cells are concentrated. Only ten percent originates from extra-adrenal sites with the organ of Zukerkandal (paraganglia along abdominal aorta) being the most common. Chromaffin ...
متن کاملPheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
OBJECTIVE The aim was to formulate clinical practice guidelines for pheochromocytoma and paraganglioma (PPGL). PARTICIPANTS The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), seven experts in the field, and a methodologist. The authors received no corporate funding or remuneration. EVIDENCE This evidence-based guideline was developed us...
متن کاملDifference in Clinical Features between Pheochromocytoma and Paraganglioma
BACKGROUND: This study investigated clinical features, management, and outcome of pheochromocytoma and paraganglioma in children and adults. METHODS: Data of 15 patients with histologically confirmed pheochromocytoma or paraganglioma from 2002 to 2010 obtained from the China Medical University Hospital database were retrospectively
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ژورنال
عنوان ژورنال: Acta Endocrinologica (Bucharest)
سال: 2018
ISSN: 1841-0987,1843-066X
DOI: 10.4183/aeb.2018.570